WHAT YOU SHOULD KNOW

ABOUT'ZESTORETIC' 10

Please read this carefully before you start to take your medicine. If you have any questions or are not sure about anything, ask your doctor or pharmacist.

The name of your medicine is 'Zestoretic'10. It contains lisinopril, which is one of a group of medicines called "angiotensin converting enzyme inhibitors" or "ACE inhibitors" for short. It also contains hydrochlorothiazide which is a diuretic. This combination of medicines is used to treat high blood pressure.

Things to remember about 'Zestoretic' 10

1 Follow your doctor's instructions on how to take your medicine and when to take it. Read the label on your medicine carefully, as it wili also tell you when to take it. Your pharmacist will be happy to help if you are not sure.

2 Keep your medicine where children cannot see it or reach it.

3 Take any tablets you don't use back to your pharmacist.

4

Like all medicines, 'Zestoretic' 10 may occasionally cause side effects in a few people. However, most problems are minor. There is some information on them on the back of this leaflet. Your doctor can also give you more information.

ZENECA Pharma

ZENECA King's Court, Water Lane

Wilmslow, Cheshire SK9 5AZ

Before takinq vour medicine

Have you had an allergic reaction or wheezing after taking an ACE inhibitor? Have you had an allergic reaction to any other medicines such as an antibiotic, a diuretic or a medicine for diabetes? Do you have kidney or liver disease? Are you taking a medicine which contains lithium? Are you taking a medicine or insulin to control diabetes? Are you pregnant or trying to become pregnant? Are you breast feeding?

H the answer is zYes’ to any of these questions, tell your doctor or pharmacist.

Taking your medicine~

Follow your doctor's instructions about taking your medicine and read the label carefuliv. Your

pharmacist will also help if you are not sure.

• Swallow the tablet with a glass of water or milk.

• Most people take 'Zestoretic' 10 once a day.

• Keep taking your medicine until your doctor tells you to stop.

• If you forget to take a dose, take another as soon as you remember, but NEVER take two days' tablets on the same day. Then go on as before.

• If you accidentally take an overdose, contact your nearest hospital casualty department or tell your doctor immediately.

Things to look out for

'Zestoretic' 10 is very effective and most people have no side effects. Occasionally some people sLlffer dizziness, headache, tiredness or a cough. More serious side effects are rare.

Stop your treatment if:

• you have severe dizziness or light-headedness: or

• you get wheezing; or

• you get a possible allergic reaction, such as swelling of the face, lips and mouth; or

• you react badly in any other way. See your doctor as soon as possible.

Storing your medicineJ

Keep your tablets in a safe place where children cannot see them or reach them. Your tablets could harm them. H vou have anv tablets left over. take them back to the Dharmacist. Oniv keeD them if vour doctor tells

vou to.

What's in vour medicine?

'Zestoretic' 10 tablets are peach coloured and they contain 10 mg of lisinopril and 12.5 mg of hydrochlorothiazide. The tablets also contain the following ingredients which have no effect: calcium hydrogen phosphate, iron oxide, magnesium stearate, maize starch and mannitol.

g Further information

This leaflet does not contain the complete information about 'Zestoretic' 10. If you have any questions or are not sure about anything, your doctor or pharmacist will be happy to help. Remember: This medicine is for you. Never give it to someone else. It may harm them even if their symptoms are the same as yours.

The information on this leaflet applies only to 'Zestoretic' 10.

'Zestoretic' 10 is manufactured by:

ZENECA Limited

Macclesfield

Cheshire

United Kingdom

'Zestoretic' is a trademark.

and

ZENECA Pharma

Zone Industrielle

La Pompelle

51064 Reims Cedex

BP401

France

ZENECA

P2131204