If the answer is ‘yes' to either of these questions, tell your doctor or pharmacist.

Pregnant women should take medical advice before exposing themselves to the risk of malaria and should consult their doctor before taking any drug to prevent malaria

Follow your doctor's or pharmacist's instructions about when and how to take your medicine. Also read the label. Your pharmacist can help if you are not sure.

The usual dose for adults is two tablets (200 mg) daily.

You may be advised to take a tower dose if you have kidneys that are not working properly.

The usual doses for children are:

Under 1 year : ¼ tablet (25 mg) daily

(including breast-fed babies)

1 - 4 years : ½ tablet {50 mg} daily

5 - 8 years : 1 tablet (100 mg) daily

9 - 14 years : 1½ tablets (150 mg) daily

Over 14 years : Adult dose daily

The daily dose is best taken with water, after food, at the same time each day For a young child, the dose may be given crushed and mixed with milk, honey or jam.

Prophylaxis with 'Paludrine' should begin at least 24 hours before entering a malarious area and must be continued during your stay and hr 4 weeks after leaving the area.

People who live permanently in malarious areas may acquire partial immunity to malaria and they should obtain individual medical advice before starting malaria prophylaxis.

If you forget to take a dose, take it as soon as you remember end then carry on as before.

If 'Paludrine' has been swallowed by accident or if an overdose has been taken, seek medical advice.

As with all medicines, undesirable events can sometimes be experienced with 'Paludrine'. Mild temporary stomach upsets may occur occasionally Mouth ulcers and inflammation of the mouth occur rarely Isolated cases of skin reactions and temporary hair loss have been reported in association with the use of 'Paludrine'.

Do not be alarmed by this list of possible events. Most people take 'Paludrine' without any problems.

If you get any other undesirable events or if you think your medicine is causing any problems, tell your doctor or pharmacist.

Check the expiry date on the canon and don't use the medicine after that date.

Keep your medicine in a safe place where children cannot see it or reach it. Your medicine could harm them.

Keep your medicine below 30°C.

Date of preparation of leaflet: May 1995

Malaria can be fatal. It is essential to take medical advice on which antimalarial drugs are appropriate. For some countries 'Paludrine' may not be suitable or may have to be taken with another drug to give maximum protection.

No medication can be guaranteed to protect against malaria in every case. Any traveller becoming ill either when visiting a malarious region or after returning home should suspect malaria and seek medical advice as soon as possible.

In addition to taking antimalarial drugs it is advisable to take other measures. Protect against mosquito bites by wearing light-coloured long-sleeved clothing and long trousers, when out of doors after sunset. Use insect repellent creams on pans of the body not covered by clothing. Sleep in a properly screened room or under a mosquito net. Spray to kill any mosquitos that may have entered rooms in spite of screening.

This leaflet does not contain the complete information on 'Paludrine'. If you have any questions, or are not sure about anything, ask your doctor or pharmacist.

The information applies only to 'Paludrine'.

2/IF/UK/1019067 P 2139802