Cyclo-Progynova 1 mg must also be stopped at once if you become pregnant, or it you develop jaundice, or your doctor finds your blood-pressure to be significantly raised or if you notice an increase in epileptic seizures.

If you have fibroids of the womb these may grow during treatment. You should stop taking Cyclo-Progynova 1 mg if your doctor finds this has happened.

Ask your doctor for advice on whether you should stop taking the tablets if you are confined to bed or have an accident or illness, or you need an operation.

• Some drugs e. g. antibiotics and antiepileptics may reduce the effectiveness of Cyclo-Progynova 1 mg.
• If you have to take other medicines regularly, you should inform your doctor.
• If you are diabetic your doctor may alter the dose of medicine required to treat your diabetes.
• Oral contraceptives should not be used. Consult your doctor for contraceptive advice.
• If in doubt about any medicines you are taking, ask your doctor

About the pack:

The pack of Cyclo-Progynova 1 mg is designed to help you remember to take your medicine. To use it you must first know the day of the week on which you will take the first tablet. If you are still having periods, take the first tablet on the fifth day of your period, whether the period has finished or not. If your periods have become infrequent or have

stopped altogether, your doctor may have advised you to start Cyclo-Progynova 1 mg immediately. In addition to the memo-pack (which contains the tablets), the outer carton contains a self--adhesive blue sticker showing the days of the week. Peel the circular sticker off its backing and stick it in the centre of the memo-pack so that the day on which you start taking the tablets is directly underneath the red segment marked "Start".

For instance, it you are to start the tablets on a

Wednesday, then stick a "Wed" directly underneath the red segment marked "Start"". You can now see on which day you have to take each tablet. Simply take one tablet each day, following the directions of the arrows, until the pack is empty. This means that you will be taking one beige tablet for the first 11 days and then one pale brown tablet daily for the following 10 days. If, at any time, you are in doubt whether you have taken your tablet, a glance at the appropriate day on the memo-pack will tell you.

When you have finished your first pack, you must leave a tablet-tree interval of seven days (unless your doctor decides otherwise). During this week, bleeding similar to a period should occur.

Start your next pack of Cyclo-Progynova 1 mg immediately after this seven-day break, whether the bleeding has stopped or not. You will in fact start on the same day as you started the previous pack, and the same will be true for each successive pack.

It is best to take your tablet at the same time each day, preferably after a meal. The tablet should not be chewed or sucked, but swallowed whole.

• Take it as soon as possible, and take the next one at your normal time.
• But it you are more than twelve hours late, leave the forgotten tablet in the pack. Continue to take the remaining tablets at the usual time on the right days.

• There have been no reports of ill-effects from overdosage. You should consult your doctor who will be able to advise you what action, if any, is necessary.

• If you are still menstruating, you will probably have bleeding regularly, 2-3 days after finishing

each pack of Cyclo-Progynova 1 mg. it you miss a period, the possibility of pregnancy should be investigated. Ask your doctor what to do.

• If you have finished your periods, Cyclo-Progynova 1 mg will probably cause you to bleed again after the end of each pack, but may not always do so.
• If bleeding occurs during the three weeks in which you are taking the tablets, let your doctor know. It is not necessary to stop tablet-taking unless your doctor says so.

Just as with normal periods, the amount of bleeding with Cyclo-Progynova 1 mg varies from woman to woman. Usually the bleeding is not unduly heavy, and it may even be rather scanty, but this is not important as tar as the treatment is concerned. It you have recently had very light, short periods, you may have rather heavier bleedings with Cyclo-Progynova 1 mg.

During the first few months of treatment you may experience some vaginal bleeding at unexpected times (breakthrough bleeding and spotting) and some breast tenderness or enlargement. These symptoms are usually temporary and normally disappear with continued treatment. It they don’t, contact your doctor.

The following symptoms, which may or may not have been caused by Cyclo-Progynova 1 mg, have been reported: indigestion, nausea, vomiting, bloated stomach, increased appetite, Increased or reduced weight, leg pains, fluid retention, palpitations, dizziness, anxiety, headaches, depressive moods, rashes, altered sexual interest.

Tell your doctor if you have any of these symptoms,

or, indeed, any other symptoms, while you are taking Cyclo-Progynova 1 mg.

It is best to take your tablet at the same time each day, preferably after a meal. The tablet should not be chewed or sucked, but swallowed whole.

Expiry date: The expiry date is printed on the pack. Do not use after this date.

Storage: Keep out of the reach of children.

29 November 1995