ADENOSCAN®

ADENOSCAN^®

(Adenosine)

PATIENT INFORMATION LEAFLET

This leaflet provides a summary of the information about the product. If you have any questions or are not sit, about anything ask your doctor.

What is in this product?

Each 10m vial of Adenoscan contains 30 mg of adenosine. This is in an isotonic solution of Sodium Chloride in Sterile Water for Injections.

Adenoscan is a sterile solution for infusion into a vein.

Adenoscan increases the amount of blood flowing through the heart muscle.

Adenoscan is manufactured by:

Sanofi Winthrop Industrie

1 Rue D'Abbaye

Notre Dame De Bondeville

France

The Product Licence holder is:

Sanofi Winthrop Ltd

One Onslow Street

Guildford

Surrey GU1 4YS

What is it used for?

Adenoscan increases the amount of blood flowing through the heart muscle during assessment of heart conditions.

Before use

You should not be given Adenoscan if:

You suffer from asthma.

You know you are allergic to adenosine.

Patients with certain heart conditions should not be given Adenoscan. Patients with other heart conditions may need special care when Adenoscan is given. Heart conditions should be discussed with a specialist before your heart scan s arranged.

If given with some medicines, food or drinks the effects of Adenoscan may be changed. Please check with your doctor if you are taking any of the following:

Dipyridamole

Drugs for asthma or bronchitis

You should not drink tea, cola, coffee or cocoa. or eat chocolate for at least 12 hours before your scan.

Method of use

Adenoscan is given as a single administration into a vein just before the scan.

The usual quantity is 140 micrograms for every kilogram of your body weight, per minute, over a period of 6 minutes.

Effects you may notice during administration.

Whilst it is acting on your heart, Adenoscan often causes other effects which you may notice. There is no need to worry, but you should tell the doctor if these occur. If the effects become worse the doctor may reduce the dose or stop the infusion. The effects typically settle within seconds or minutes after the infusion. Symptoms which have been reported include:

Most commonly

Flushing, headache, dizziness, light headedness, chest pain, chest pressure, urge to breathe deeply, discomfort in stomach. neck, throat or jaw

Less common

Sweating, a congested nose, nipple discomfort, nervousness, weak arms or legs, tremors, drowsiness, a buzzing or ringing in the ear, blurred vision, dry mouth, a metallic taste, discomfort in the leg, arm or back, weakness or urinary urgency, slow heart beat.

Expiry date; do net use after the expiry date shown on the vial. Do not refrigerate Any portion of vial not used at once should be disposed of.

This leaflet does not contain all the information about your medicine. Pharmaceutical companies are not able to discuss your personal medical conditions so if you have any questions, or you are not sure about anything ask your doctor

301/227