Please read this leaflet carefully before you start to take this medicine. If you do not understand it or you want to know more, ask your doctor or pharmacist. Keep the leaflet, you may want to read it again.

The name of your medicine is Euglucon 5mg Tablets. Each tablet contains 5mg of the active ingredient, Glibenclamide BP.

The tablets also contain lactose, maize starch, aerosil, talc, magnesium stearate and purified water.

Euglucon is available in blister packs of 28 or 100 tablets.

Glibenclamide, the active ingredient, belongs to a group of medicines called 'oral hypoglycaemic agents'. They act to lower the amount of sugar in your blood.

The marketing authorisation for Euglucon 5mg tablets is held by Roussel Laboratories Ltd, Broadwater Park,

Orbital Road, Denham, Uxbridge, Middlesex UB9 5HP. It is manufactured by Roussel Laboratories Ltd, Covingharn

Swindon, Wiltshire SN3 5BZ.

Your doctor has diagnosed that you have too much sugar in your blood (or diabetes mellitus). Even though you have kept to a low sugar diet, it is still too high and you need to take the tablets to keep it as low as possible. You must stick to your recommended diet while taking the tablets. Taking the tablets does NOT mean you can ignore

the dietary advice given to you.

Before you take Euglucon tablets, please read the following statements.

• You have very high blood sugar levels, as happens in uncontrolled diabetics needing insulin
• You suffer from certain other illnesses, such as liver, adrenal gland, kidney or thyroid problems
• You are pregnant or breastfeeding
• You are under the age of 14
• You have suffered a severe reaction to these or tablets of a similar type in the past

If you think that any of these apply to you, DO NOT start the tablets - go back and discuss it with your doctor.

Euglucon and other medicines that you may be taking sometimes affect each other's action. This may result in an increase or a decrease in your sugar levels.

This is especially so if you use pain-killers such as aspirin or any cough or cold remedies or are taking medication;

for any of the following conditions:-

High blood pressure

Asthma

Heart problems such as angina

High cholesterol levels

Anything to suppress (decrease) your appetite

Thyroid problems

Rheumatism

Gout

Cancer

Depression or any emotional problem

To thin your blood and stop it clotting easily (anticoagulants, such as warfarin)

Contraception (the pill or mini-pill)

Any bacterial infection (antibiotics)

Your doctor may need to change your dose of Euglucon because of your other medicines.

Some other conditions, particularly feverish illnesses such as bronchitis or 'flu, other infections or injury can affect your blood sugar. If you have such an illness consult your doctor, you may need extra treatment.

NOTE: If you become pregnant, you may need other treatment for your diabetes such as insulin. You may restart Euglucon after the baby is born. Your doctor will advise you about this.

A low blood sugar (hypoglycaemia), which may occur from time to time in some patients, may cause light-headedness, a pounding heart, clamminess or sweaty palms. If you experience the symptoms of low blood sugar, you should not drive or operate machinery. Your doctor will give you further advice. If your blood sugar is stabilised, you may drive or operate machinery.

Always take the number of tablets your doctor has asked you to take. At first this will be half a tablet or a single one. This will usually be taken once a day.

If you are changing the type of medicine used to treat your diabetes, your doctor will give you instructions. To start with you may have to take both types together.

Your doctor may increase your dose if the blood sugar level does not come down enough. You should not take more than your doctor tells you.

Euglucon tablets should be taken with or immediately after food. This will usually be with breakfast or the first main meal of the day.

If you take too many tablets by accident, you must take 3-4 sugar lumps dissolved in water to balance the effect of the tablets. You can repeat this if you feel it is necessary after 15 minutes. If you still feel unwell, consult your doctor straight away.

It is very important that you do not miss a dose. You should try not to miss any tablets, since high blood sugar can cause problems. If you do miss one, take it as soon as possible with food. However, if it is almost time for your next dose, skip the missed dose and carry on as normal. Do not take an extra tablet to make up.

Like all medicines, Euglucon may cause you some problems. These are rare, and usually minor, for example tummy upsets, slight sickness, decreased appetite (anorexia) or diarrhoea, and usually disappear with time. Your skin may feel itchy and develop a rash.

Sometimes people taking Euglucon may find that they feel more tired and unwell than usual. Others may notice that they bruise or bleed more easily if they cut themselves. Please tell your doctor if you notice any of these effects. Your doctor may want to perform regular blood tests to monitor your medical condition. If this is so, do not worry, it is just routine.

Very rarely, people have become jaundiced (yellowing of the skin) or developed liver problems such as hepatitis during treatment with Euglucon. If you notice this, stop taking the tablets, tell your doctor immediately.

If you have any other problems and think that your medicine may be causing them, tell your doctor or pharmacist.

NOTE: light-headedness, a pounding heart, clamminess or sweaty palms may mean that your blood sugar is too low and the dose of Euglucon is not right for you. If you think this is happening to you, or you think you are reacting badly in any other way, STOP taking the tablets and contact your doctor or pharmacist straight away.

Do not use your medicine after the expiry date shown on the label.

Keep it in the pack in which it was given to you. Do not transfer your medicine to another container.

Keep this medicine in a safe place where children cannot get at it. Your medicines could harm them.

If your doctor tells you to stop your treatment, return any left over to the pharmacist. Only keep it if the doctor tells

you to.