Please read this leaflet carefully before you receive any dose of Cerubidin. This leaflet is a summary of important information about Cerubidin. If you have any questions, or are not sure about anything to do with your treatment, ask your doctor, pharmacist or nurse for more information. Keep this leaflet in a safe place. You may want to refer to it again.
WHAT IS CERUBIDIN INJECTION ?
- The active ingredient in Cerubidin is daunorubicin hydrochloride . Each vial contains 20 mg of daunorubicin.
- Each vial also contains mannitol.
- Cerubidin injection is available in packs of 1 and 10 vials.
- Daunorubicin is an anthracycline glycoside, an antIeukaemic agent.
WHO MAKES CERUBIDIN INJECTION ?
- The Product Licence holder is May & Baker Limited, Eastbourne, East Sussex a member of the Rhône-Poulenc Rorer group of companies.
- Cerubidin is manufactured by: Rhône -Poulenc Rorer Propharm, 180, Rue JEAN Jaurès, Maisons-Alfort, France a member of the Rhône -Poulenc Rorer group of companies.
WHY HAVE YOU BEEN PRESCRIBED CERUBIDIN INJECTION ?
- Cerubidin (daunorubicin) is used in the treatment of acute leukaemia. Leukaemia is a disease of the special cells in your body which produce the various components of your blood. This generally results in some or many of the following signs and symptoms: increased counts of white cells in the blood, anaemia, easy bruising and nose bleeds, exhaustion, bone and joint pain, headaches, severe infection and fever.
Daunorubicin attacks and destroys these diseased cells. Unfortunately, the growth of normal cells are also affected. This may result in some of the side effects which are discussed later in this leaflet. Before treatment, you should discuss the risks and benefits of this medicine with your doctor.
- As with other chemotherapeutic agents, your doctor may have prescribed daunorubicin for other reasons.
BEFORE RECEIVING ANY DOSE OF CERUBIDIN. YOU SHOULD CONSIDER THESE QUESTIONS
- If the answer is YES to any of these questions, you should probably not receive Cerubidin. Please discuss the matter with your doctor immediately. However, your doctor may decide that your treatment is essential.
- do you have, or have you been in recent contact with anyone who has chicken pox or herpes zoster ("shingles") ?
- do you have an infection, fever or high temperature ?
- are you pregnant ?
- are you breast feeding ?
- do you have a lot of mouth ulcers ?
2. If the answer is YES to any of these ;questions, it is important that you discuss the matter with your doctor BEFORE receiving Cerubidin.
- are you sensitive to or allergic to Cerubidin ?
- have you received radiation therapy to the chest ? have you received any other medicines to treat leukaemia (or cancer) ?
- do you have any heart problems ?
- do you have a history of gout ?
- do you have a history of kidney stones ?
- do you have any other kidney problems ?
- do you have any liver problems ?
HOW WILL CERUBIDIN INJECTION BE ADMINISTERED TO YOU ?
The injection will be given into one of your veins over a period of about 20 minutes.
The injection should never be given as a deposit under the skin or into a muscle. The site
of injection should not be covered or bandaged.
If you experience any pain, swelling or warmth around the vein where Cerubidin is being
injected, inform your nurse or doctor IMMEDIATELY.
