‘Cozaar’ ™ Tablets 50mg ‘Cozaar’ ™ Half Strength Tablets 25mg

(losartan potassium) (losartan potassium)

PLEASE READ ALL OF THIS LEAFLET CAREFULLY BEFORE YOU START TO TAKE YOUR TABLETS, EVEN IF YOU HAVE JUST HAD A REPEAT PRESCRIPTION. SOME OF THE INFORMATION IN YOUR PREVIOUS LEAFLET MAY HAVE CHANGED.
Keep this leaflet. You may want to read it again.
WHAT IS IN YOUR TABLETS?

Active ingredients: The active ingredient in ‘Cozaar’ and ‘Cozaar’ Half Strength Tablets is losartan potassium. ‘Cozaar’ is available as white, oval, scored tablets marked 952 containing 50mg of losantan potassium. ‘Cozaar’ Half Strength is available as white, oval tablets marked 951 on one side and plain on the other, containing 25mg of losartan potassium.

Other ingredients: Hydroxypropylcellulose EP; hydroxypropylmethylcellulose EP; lactose EP: magnesium stearate EP: microcrystalline cellulose EP; pregelatinised starch BP: titanium dioxide EP

Although ‘‘Cozaar’ and ‘Cozaar’ Half Strength contain a very small amount of potassium, they cannot replace potassium supplements. If your doctor has prescribed potassium supplements, continue to follow his or her advice

‘Cozaar’ Tablets are supplied in packs of 28 tablets ‘Cozaar’ Half Strength Tablets are supplied in packs of 7 tablets.

HOW DO YOUR TABLETS WORK?

‘Cozaar’ belongs to a group of medicines known as angiotensin-II receptor antagonists. Angiotensin II is a chemical occurring in the body,

which tightens your blood vessels making it harder for the blood to pass through them and causing your blood pressure to increase. ‘Cozaar’ blocks this effect of angiotensin II, causing the blood vessels to relax, and so lowers your blood pressure.

WHO MAKES YOUR TABLETS?

Your tablets are made by Merck Sharp & Dohme Limited, Hertford Road, Hoddesdon, Hertfordshire, UK, who hold the Product Licence in the UK.

WHY DO YOU NEED TO TAKE THESE TABLETS?

Your doctor has prescribed ‘Cozaar’ because you have a condition known as hypertension or high blood pressure

Blood pressure is the term given to the pressure produced by your heart pumping blood to all parts of your body. Your blood pressure is measured by two numbers, e.g. 120/80 mm Hg. The top number measures the pressure while your heart beats and the bottom number measures the pressure in between heart beats.

Normal blood pressure is part of good health. High blood pressure is caused when the blood vessels tighten and the measurement goes above the normal range for your age. There are usually no symptoms of high blood pressure and you will only know you have it if you have had your blood pressure measured.

Although you might feel quite well, if your high blood pressure is not treated, it can damage your heart and kidneys, and in some cases lead to strokes, heart attacks, heart and kidney failure, or blindness

High blood pressure can be treated and controlled with medicines such as ‘Cozaar’ . Your doctor may also recommend that you make some changes to your lifestyle to help your high blood pressure, such as losing weight, avoiding alcohol and smoking, and reducing the amount of salt in your diet. Your doctor may also encourage you to take more mild exercise

ARE THERE PATIENTS WHO SHOULD NOT TAKE THESE TABLETS?
Yes, do not take the tablets if:

You are or think you may be pregnant.

You are planning to become pregnant

You are breast feeding.

You are allergic to any of the ingredients.

‘Cozaar’ should not be given to children

If you think any of these apply to you, do not take the tablets. Talk to your doctor first and follow the advice given

WHAT ELSE SHOULD YOU KNOW BEFORE TAKING 'COZAAR'?

It is important to tell your doctor before taking 'Cozaar' if you suffer from liver or kidney problems.

Tell your doctor if you have recently suffered from excessive vomiting and/or diarrhoea.

You should tell your doctor if you suffer from lactose intolerance as lactose is one of the ingredients in 'Cozaar' and 'Cozaar' Half Strength' Tablets.

CAN YOU TAKE 'COZAAR' WITH OTHER MEDICINES?

'Cozaar' does not usually interact with food or most other medicines you may be taking. You should, however, tell your doctor if you are taking potassium supplements, potassium-sparing agents, or potassium-containing salt substitutes. Your doctor will decide whether you should take these agents with 'Cozaar'. You should also tell your doctor about all medicines that you are taking or plan to take This includes any medicines obtained without a prescription.

HOW SHOULD YOU TAKE 'COZAAR'?

You must keep taking 'Cozaar' every day and exactly as your doctor has told you. It is important that you take 'Cozaar' for as long as your doctor prescribes it in order to keep your blood pressure controlled. The usual dose of 'Cozaar' for most patients is one 50mg tablet once a day to control blood pressure over the 24
hour period. However, in certain patients such as those
over 75 years of age or those with kidney or liver problems, the doctor may prescribe a lower dose of 25mg (i.e. 'Cozaar' Half Strength) once a day

Alternatively, the doctor may prescribe a higher dose

(i.e. 2 x 50mg tablets). Follow your doctor s instructions exactly

IMPORTANT- For patients starting treatment with ‘Cozaar’ Half Strength (i.e. 25mg/day):

You must ensure that you make an appointment to see your doctor before you finish the 7-day pack, in order to get your blood pressure measured and check that you are receiving the correct dose.

You can take ‘Cozaar’ with or without food. It is recommended that you take your tablet at the same time each day.

WHAT IF YOU FORGET TO TAKE A TABLET OR TAKE TOO MANY?

Try to take ‘Cozaar’ daily as prescribed However, if you miss a dose, just carry on with the next dose as normal. Do not take an extra tablet to make up

If you take too many tablets by mistake, contact your doctor immediately
WHAT UNWANTED EFFECTS COULD 'COZAAR' HAVE?

Although most people find that ‘Cozaar’ is suitable for them, like all medicines, it can occasionally cause unwanted effects (side-effects) in some people. Side-effects are generally rare, but those seen most often are dizziness or light-headedness and rash. If you notice any of these effects, or you have any other unusual symptoms or feelings, contact your doctor or pharmacist promptly.

It will help if you make a note of what you experienced, when it started and how long it lasted.

HOW SHOULD YOUR TABLETS BE KEPT?

Keep your tablets out of the reach of children.

Store them in a dry place at room temperature and avoid temperatures above 30°C (86°F).

Do not put the tablets into another container, they might get mixed up. Do not remove the tablets from the blister pack until you are ready to take the medicine.

Do not take the tablets past the expiry date, which is clearly marked on the pack.

REMEMBER: This medicine is for you Do not share it with anyone else It may not suit them.

Date of issue: December 1994
HOW CAN YOU OBTAIN MORE INFORMATION ABOUT 'COZAAR'?

This leaflet gives you only some of the most important patient information about Cozaar If you have any questions after you have read it, ask your doctor or pharmacist, who may give you further information

™ denotes trademark of E.I du Pont de Nemours and Company, Wilmington, Delaware, USA.