Potaba is part of the Vitamin B complex. It is a naturally occurring substance that participates in many biologically important processes.

Potaba is prescribed for conditions such as scleroderma and Peyronie’s disease. It is believed to produce a skin/plaque softening in patients when given in adequate dosage over sufficient time.

Understanding of drug mechanism at the cellular level is incomplete in the case of many medications. It is thought that Potaba has an antifibrotic effect due to increased oxygen uptake at the tissue level.

Orally, according to the schedule contained in this leaflet.

Therapy with Potaba is non-toxic, low-risk treatment for conditions that are usually long-term. This regimen represents a good possibility of softening hardened tissue. As there is a very low incidence of drug interactions, many other medications may be continued while you are taking Potaba. It is highly soluble in water and therefore readily absorbed.

Potaba is available on prescription from your doctor and at your local pharmacy.

Your doctor should know if you are taking antimicrobial sulphonamides as Potaba may nullify the antibacterial effect.

Potaba should be administered with caution in the following medical conditions:

Diabetes mellitus (sugar diabetes)

Hypoglycaemia (chronic low blood sugar)

Allergy to Potaba or PABA

Kidney disease

Length of therapy varies considerably with disease state and from person to person. It may be two to three months before results are noticeable.

Potaba therapy is most acceptable when taken in conjunction with meals or snacks. There are no

specific foods to avoid, but it is good to keep a normal dietary intake to prevent stomach upset or low blood sugar. The doctor should know if you are on a special diet. Usual activities can be encouraged. If you are pregnant, planning to become pregnant, or nursing an infant your doctor should be notified so this can be taken into consideration when prescribing Potaba or any prescription medication.

Anorexia, nausea, fever and rash occurred rarely.

Notify the doctor, stop taking the medication until symptoms subside. The doctor may then write a schedule to accomplish desensitization* and resume therapy.

* Desensitization schedules are available from Glenwood Ltd.

With any prescription drug it is wise to consider:

The prescription is for the specific condition and for the use of the patient only.

Keep medicine out of reach of children.

If you have questions about the information presented here, ask your doctor, pharmacist or nurse.

Potaba is taken four times a day after meals or snacks. If you are unable to eat, omit dosage until eating again.

Potaba is supplied in three dosage forms: Envules^®, Capsules and Tablets. Changing dosage form may prevent medication burn-out. (Medication burn-out is a term to describe a situation in which the patient stops taking medication. In consequence, the desired results of therapy will not be seen.)

Add one envelope to a glass of chilled water or juice; stir to dissolve and drink after eating.

Take six capsules after eating with a glass of water.

CRUSH six tablets and add to a glass of chilled water or juice; stir thoroughly and drink after eating.

Raynaud’s & Scleroderma Association

112 Crewe Road

Alsager

Cheshire ST7 2JA

Telephone: (01270) 872776