• What your tablets do

Zofran tablets contain ondansetron which belongs to a group of medicines called anti-emetics Some medical treatments can make you feel sick or be sick (nausea and vomiting) - Zofran tablets may stop these effects.

IF YOU ARE NOT SURE WHY THEY HAVE BEEN PRESCRIBED FOR YOU, ASK YOUR DOCTOR.

• Before taking your tablets
• Have you been told you are allergic to Zofran or similar medicine?
• Do you think you may be pregnant?
• Are you breast feeding?

IF THE ANSWER TO ANY OF THESE QUESTIONS IS YES:

• Did you tell your doctor at the last visit or an earlier visit?

IF YOU DID NOT TELL YOUR DOCTOR THEN YOU SHOULD DO SO AS SOON AS POSSIBLE AND BEFORE STARTING THE MEDICINE.

Your doctor will advise you about taking the medicine.

• Look at the label

It should say WHO should take them, HOW MANY and WHEN If it doesn't or you aren't sure, ask your doctor or pharmacist.

(If prescribed for a CHILD, make sure the tablets are taken as the label says).

• How to take your tablets

Swallow each tablet whole with a little water.

• After starting to take your tablets

Zofran tablets should start to work within one or two hours of taking a dose. If you vomit a dose back within one hour then take the same dose again - otherwise do not take more tablets or take them more often than the label says. If you continue to feel sick then tell your doctor.

Most people find taking these tablets causes no problems As with most medicines, a few people may find they have side effects. See the back of this leaflet for more information.

• Where to keep your tablets

Keep Zofran tablets safely away from children. A child may be harmed by medicine prescribed for someone else Keep them at room temperature.

More information on ZOFRAN TABLETS

• What your tablets contain

Each yellow, oval tablet contains:

The active ingredient ondansetron 4mg or 8mg

Other ingredients include lactose, starch. microcrystalline cellulose, magnesium stearate,

hydroxypropylmethylcellulose (E464) titanium dioxide (E171 ) and iron oxides (E172)

• Side effects

Along with its needed effects, a medicine may cause unwanted effects Most people taking this medicine find it causes no problems.

A few people can be allergic to some medicines; if any of the following side effects come on soon after taking these tablets, stop the tablets and tell your doctor immediately:

Also check with your doctor as soon as possible if any of the following side effects occur:

If you feel unwell or have any other unusual discomfort you don't understand, it is important to tell your doctor as soon as possible

• What to do if you miss a dose

If you miss a dose and feel sick or vomit, take a tablet as soon as possible and then carry on as before.

If you miss a dose but do not feel sick take the next dose as on the label.

• What to do if you take too many tablets

It is important to stick to the dose on the label Taking more than this could make you ill If an overdose is taken, don't delay, ask your doctor what to do or contact your nearest hospital casualty department.

• Breast feeding

The ondansetron in Zofran tablets probably passes into the mother's milk It is better therefore that mothers taking Zofran tablets do NOT breast feed.

• If you don't feel better

If your sickliness does not get better while taking Zofran then TELL YOUR DOCTOR.

• What to do with any unused tablets

If your doctor stops your treatment, do not keep any leftover tablets unless your doctor tells you to Return any unused tablets to your pharmacist Do not use the tablets after the expiry date on the tablet foil or carton.

• Remember

This medicine is for YOU Only a doctor can prescribe it for you Never give it to someone else There may be good reasons why it could harm that person.

• Further information

This leaflet does not contain all the information about your medicine If you have any questions or are not sure about anything, ask your doctor or pharmacist who has the information you need and will advise you Pharmaceutical Companies are not allowed to answer questions from patients about their diseases You may well be able to find out more about prescribed medicines from books in public libraries.

This leaflet has been produced in accordance with guidance issued by the Association of the British

Pharmaceutical Industry The information provided applies only to ZOFRAN TABLETS.

Zofran is a trade mark

Product Licence held by Glaxo Pharmaceuticals UK Limited, Stockley Park, England

Manufactured by Glaxo Pharmaceuticals UK Limited, Speke, Liverpool, England

Leaflet written August 1993

Glaxo Laboratories Limited, Stockley Park West, Uxbridge, Middlesex UB11 1BT 1093