Sumatriptan succinate tablets

Please read this carefully before starting to take your medicine.

Each long pink tablet contains: The active ingredient - sumatriptan 50mg (as the succinate) Other ingredients - lactose, microcrystalline cellulose, croscarmellose sodium, magnesium stearate, methylhydroxypropylcellulose, titanium dioxide (E171), triacetin and iron oxide (E172) Packs contain 6 or 12 tablets in blister strips of 6 tablets.

Product Licence held by Glaxo Pharmaceuticals UK

Ltd, Stockley Park, England, UB11 1BT

Manufactured by Glaxo Pharmaceuticals UK Limited,

Speke, Liverpool, England

Imigran-50 tablets contain sumatriptan, the first of a new group of medicines developed for the treatment of migraine. The symptoms of migraine may be due to swollen blood vessels around the brain. Medicines like Imigran probably work by reducing the size of these blood vessels and are called 5HT₁, receptor agonists.

heart disease such as –

high blood pressure

disease of the liver

or kidneys or

• If you are taking any medicines for your migraine which contain ergotamine, (If so, you should stop taking them at least 24 hours before taking Imigran-50 tablets), or
• If you are taking any medicines on a doctor's prescription for the treatment of depression or to help you lose weight, or
• If you are pregnant, or likely to become pregnant, or breast feeding, or
• If you are over 65 years of age, or
• If you have a family history of heart disease.

Does the doctor who prescribed it know this?

Even so your doctor may still want you to take them.

You should also talk to your doctor before using these tablets if you have been told you have sugar diabetes, or a high blood cholesterol or if you are a regular cigarette smoker or if you are very overweight.

Your doctor will advise you about taking the medicine .

Look at the label - It should say WHO should take them, HOW MANY and WHEN If it does not or you are not sure, ask your doctor or pharmacist or follow this advice:

At the first signs of a migraine attack take ONE tablet If this does not make your migraine better do NOT take any more tablets for this attack If your migraine goes then comes back you may take another tablet .

Some people find they need to take TWO tablets for each attack instead of ONE.

Whichever dose is taken DO NOT TAKE MORE THAN 6 tablets in any 24 hour period, that is 300mg in total. Swallow each tablet whole with a little water. Do not chew or crush them.

There is little experience of Imigran in children or those over 65 years of age so it is not usually prescribed for these age groups.

• What to do if you take too many tablets

It is important to keep to the dose on the label. Taking more than this could make you ill. If an overdose is taken, DO NOT DELAY, ask your doctor what to do or contact your nearest hospital emergency department.

Within an hour or two of taking a dose most people find their migraine is much better. If this does not ease your migraine, then you may take your usual 'pain killers', provided they do not contain ergotamine. Wait at least six hours after taking an Imigran-50 tablet before taking any medicines containing ergotamine.

Most people find taking this medicine causes no problems. As with most medicines, a few people may find they have side-effects to it.

More information on IMIGRAN-50 TABLETS

Along with its needed effects, a medicine may cause unwanted effects. Most people taking this medicine

find it causes no problems.

Check with your doctor immediately if any of the following side-effects occur:

Sudden wheeziness, fluttering or tightness in the chest Swelling of eyelids, face or lips

Skin rash - red spots or hives (skin lumps)

If you notice any of these side-effects it may be that you are allergic to the medicine.

Do not take any more of the tablets unless your doctor tells you to do so.

A few people may notice the following side-effects:

Feelings of tingling, warmth, heaviness, pressure, tightness or sometimes pain in different parts of the body, including the chest or throat; although sometimes very strong they usually pass off in a few minutes. If they continue or are particularly severe (especially chest pain) tell your doctor immediately. Do NOT take any more tablets; your doctor will decide if you should stop using them.

Also;

Tiredness or sleepiness (IMPORTANT if you are driving or working a machine)

Dizziness

Flushing (redness of face lasting a few minutes) Feeling of weakness

Feeling sick (nausea) or being sick (vomiting) - when not part of migraine attack.

These are not usually very troublesome and pass off with time. There is no need to stop treatment unless you find them too unpleasant.

If you feel unwell or have any other unusual discomfort you don't understand it is important to tell your doctor as soon as possible.

If you do not get satisfactory relief of your migraine by taking Imigran-50 tablets then tell your doctor at

your next visit.

in case you feel a migraine attack coming on.

Keep the tablets away from heat (below 30°C/86°F)

which could spoil them.

As with all medicines, keep Imigran-50 tablets safely

away from children. A child may be harmed by

medicine prescribed for someone else.

If your doctor stops your treatment do not keep any left over tablets unless your doctor tells you to. Return any unused tablets to your pharmacist for safe disposal .

Do not use Imigran-50 tablets after the expiry date printed on the carton or foil but return them to your pharmacist.

This medicine is for YOU. Only a doctor can prescribe it for you. Never give the tablets to someone else. There may be reasons why they could harm that person.

This leaflet does not contain all the information about your medicine. If you have any questions or are not sure about anything, ask your doctor or pharmacist who has the information you need and will advise

Pharmaceutical Companies are not allowed to answer questions from patients about their diseases.

There are two national organisations which offer both help and advice on migraine:

The British Migraine Association

178a High Road

Byfleet, Weybridge

Surrey KT14 7ED

Telephone: 0932-352468

The Migraine Trust

45 Gt. Ormond Street

London WC1N 3HD

Telephone: 071-278 2676

You may well be able to find out more about prescribed medicines from books in public libraries.

IMIGRAN is a trade mark owned by the Glaxo Group of Companies

Glaxo Laboratories Limited

Stockley Park West

Uxbridge, Middlesex UB11 1BT